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Text File  |  1987-10-07  |  556b  |  16 lines
  1.  
  2.          IN PATIENTS WITH RENAL IMPAIRMENT, CEFOTAXIME DOSAGE SHOULD
  3.          BE CAREFULLY ADJUSTED TO AVOID TOXICITY (MAY ENHANCE RENAL
  4.          IMPAIRMENT).
  5.           
  6.          SOME CLINICIANS RECOMMEND THAT THE DOSING INTERVAL BE
  7.          INCREASED BASED ON THE PATIENT'S CREATININE CLEARANCE:
  8.           
  9.                 CREATININE
  10.                  CLEARANCE          DOSING INTERVAL
  11.                 (ML/MINUTE)
  12.           
  13.                   10-50              8 TO 12 HOURS
  14.                    <10               12 TO 24 HOURS
  15.           
  16.